Comparative Metagenomics by Cross-assembly
نویسندگان
چکیده
[1] Centre for Molecular and Biomolecular Informatics, Nijmegen Centre for Molecular Life Sciences, Radboud university medical centre, Nijmegen, The Netherlands. [2] Department of Marine Biology, Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. [3] Computational Science Research Center, [4] Department of Mathematics, and [5] Department of Biology, San Diego State University, San Diego, CA, USA.
منابع مشابه
Reference-independent comparative metagenomics using cross-assembly: crAss
MOTIVATION Metagenomes are often characterized by high levels of unknown sequences. Reads derived from known microorganisms can easily be identified and analyzed using fast homology search algorithms and a suitable reference database, but the unknown sequences are often ignored in further analyses, biasing conclusions. Nevertheless, it is possible to use more data in a comparative metagenomic a...
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Comparative analysis of metagenomes can be used to detect sub-metagenomes (species or gene sets) that are associated with specific phenotypes (e.g., host status). The typical workflow is to assemble and annotate metagenomic datasets individually or as a whole, followed by statistical tests to identify differentially abundant species/genes. We previously developed subtractive assembly (SA), a de...
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Comment citer ce document : Benoit, G. (Auteur de correspondance), Peterlongo, P., Mariadassou, M., Drezen, E., Schbath, S., Lavenier, D., Lemaitre, C. (2017). Simka: large scale de novo comparative metagenomics. In: JOBIM 2017 LILLE (p. 3-5). Presented at JOBIM 2017 Journées Ouvertes Biologie Informatique Mathématiques, Lille, FRA (2017-07-03 2017-07-06). Simka: large scale de novo comparative...
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تاریخ انتشار 2015